MEDICATION RELATED PROBLEMS AND CLINICAL PHARMACIST INTERCESSION TO RESOLVE THOSE AS DIRECT PATIENT CARE PROCESS

Authors

  • Sushanta Das Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University
  • Rajesh Maheshwari Department of Pharmacy, Sumandeep Vidyapeeth Deemed to be University

Keywords:

Medication related problems, Clinical pharmacist intercession, Direct patient care, Therapeutic outcome

Abstract

Medication related problems (MRPs) are ‘any preventable event that may cause or lead to an inappropriate medication use or patient harm while the medication is in the control of the health care professional, patient or consumer’. Whereas prescribing error is an error in the choice or administration of drugs for patients including; incorrect dose or medicine, duplicate therapy, incorrect route of administration or even wrong patient. These conditions are frequent in general practice and in hospitals setup and can result in grim patient harm. Clinical Pharmacists can play a significant role by identification and modification of these errors. Thorough prescription review, timely intercession, patient interview and follow-up can reduce the quantity of MRPs. Here we discussed about five cases where definite MRPs was identified by the clinical pharmacist during medication chart review and those were thoroughly cross matched with standard reference to established as developed due to prescription error. Same were reported to the visiting doctor and subsequent modifications were suggested to resolve those issues. This case series analysis concludes that MRPs are appearing due to prescription error and that need to be addressed with proper management strategy. Support by clinical pharmacist intercession as a direct patient care process in optimizing drug therapy by providing proper medication information was highly accepted and appreciated by various doctors and has achieved enhanced therapeutic outcome.

References

Aronson, J.K. (2009). Medication errors: definitions and classification. British Journal of Clinical Pharmacology. 67(6): 599–604. doi: 10.1111/j.1365-2125.2009.03415.x).

Da costa, F.A., Silvestre, L., Periquito, C., Carneiro, C., Oliveira, P., Fernandes, A.I., et al. (2016). Drug related problems identified in a sample of Portuguese institutionalized elderly patients and pharmacists interventions to improve safety and effectiveness of medicines. Real world outcomes. 3:89-97. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4819488/ DOI: 10.1007/s40801-016-0061-x

Dean, B., Barber, N., and Schachter, M. (2000). What is a prescribing error? Quality in Health Care. 9:232–237. doi: 10.1136/qhc.9.4.232.

Dean, B., Vincent, C., Schachter, M., and Barber, N. (2005).

The incidence of prescribing errors in hospital inpatients: an overview of the research methods. Drug Safety. 28:891-900.

Foroughinia, F., Tazarehie, S.R., Petramfar, P. (2016). Detecting and managing drug related problems in the neurology ward of tertiary teaching care hospital in Iran: A clinical pharmacist intervention. J Res Pharm Pract. 5(4):285-289. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5084487/ DOI:10.4103/2279-042X.192455

Lee, T., Davis, E., and Kielly, J. (2016). Clinical impact of a pharmacist-led inpatient anticoagulation service: a review of the literature. Integrated Pharmacy Research and Practice. 5:53-63. doi: 10.2147/IPRP.S93312. eCollection 2016.

Lesar, T.S., Briceland, L., and Stein, D.S. (1997). Factors related to errors in medication prescribing. Journal of American Medical Association. 277:312–17.

Lewis III JL. (2021). Hypokalemia, (Low Level of Potassium in the Blood). Merck Manual Consumer Version. 2021 Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Kenilworth, New Jersey, USA. Available from https://www.merckmanuals.com/home/hormonal-and-metabolic-disorders/r-balance/hypokalemia-low-level-of-potassium-in-the-blood. Accessed date: July 21, 2021.

Pelligrin, E., Lee, U., Uyeno, R., Ayson, C., Goo, R. (2017). Potentially preventable medication related hospitalisations: A clinical pharmacist approach to assessment, categorization and quality improvement. J Am Pharm Assoc., 57(6):711-716

Peterson, C., and Gustafsson, M. (2017). Characterisation of Drug- Related Problems and associated factors at a clinical pharmacist service- Naïve Hospital in Northern Sweden. Drugs- Real world outcomes .4:97-107. Available from: https://www.ncbi.nlm.nih.gov/pubmed/28527149 DOI: 10.1007/s40801-017-0108-7

Pfister, B., Jonsson. J., and Gustafsson, M. (2017). Drug-related problems and medication reviews among old people with dementia. BMC Pharmacology and Toxicology. 18(1):52. doi: 10.1186/s40360-017-0157-2.

Ravn-Nielsen, L.V., Duckert M.L., Lund, M.L., Henriksen, J.P., Nielsen, M.L., Eriksen, C.S., et al. (2018). Effect of an In-Hospital Multifaceted Clinical Pharmacist Intervention on the Risk of Readmission: A Randomized Clinical Trial. Journal of American Medical Association Internal Medicine. 178(3):375-382. doi: 10.1001/jamainternmed.2017.8274.

Tranexamic Acid. (2021). Medsafe: New Zeeland Medicines and Medical Devices safety Authority. Available from https://www.medsafe.govt.nz/Profs/Datasheet/t/tranexamicacidtab.pdf. Accessed date: July 21, 2021.

Velo, G.P., and Minuz, P. (2009). Medication errors: prescribing faults and prescription errors. British Journal of Clinical Pharmacology. 67(6):624–628. doi: 10.1111/j.1365-2125.2009.03425.x

Verdoorn, S., Frans, K.H., Faber, A., Gussekloo, J., Bouvy, M.L. (2015). Majority of drug-related problems identified during medication review are not associated with STOPP/START criteria. Eur J Clin Pharmacol. 71:1255–62. Available from: https://www.ncbi.nlm.nih.gov/pubmed/26249851 DOI: 10.1007/s00228-015-1908-x

WHO. (2016). Medication errors: Technical series on safer primary care. Geneva. World Health Organization; 2016. 28p. Report no: 9. Available form: http://apps.who.int/iris/bitstream/handle/10665/252274/9789241511643-eng.pdf;jsessionid=E4D3A15C83CBF2F92C45A2381DE64CE8?sequence=1.

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Published

2026-08-28

How to Cite

Das, S., & Maheshwari, R. (2026). MEDICATION RELATED PROBLEMS AND CLINICAL PHARMACIST INTERCESSION TO RESOLVE THOSE AS DIRECT PATIENT CARE PROCESS. Suranaree Journal of Science and Technology, 29(6), 070057(1–9). retrieved from https://ph04.tci-thaijo.org/index.php/SUJST/article/view/76

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Section

Research Article