THE CURRENT STRATEGIES FOR ENHANCING ANTI-CARIES PROPERTIES OF DENTAL ADHESIVE: A REVIEW
Keywords:
Dental adhesives, Remineralization, Antibacterial, Protein repellent, Secondary cariesAbstract
Bacterial microleakage at tooth-restoration interface leading to recurrent infection or secondary caries is the main reason for resin composite restoration failure. The main reason for failure may be the lack of antibacterial and remineralizing properties of dental adhesives. This study reviewed the current strategies used in dental adhesives to enable the anti-caries effects. A total of 65 studies from identified 273 original articles published from May 2015 to May 2020 were included and reviewed. The results revealed that the most common anti-caries strategies were antibacterial strategies (76%) followed by remineralizing strategies (41%), and protein repellent strategies (12%). The most frequently used agents to promote antibacterial, remineralizing, and protein repellent effects were polymerizable quaternary ammonium compounds, nanoparticles of amorphous calcium phosphate, and protein repellent agent (2-methacryloyloxyethyl phosphorylcholine) respectively. The strategies were either single or multi-mode actions. The utilization of the additives at the designated level in the majority of the studies promoted in vitro anti-caries actions with no detrimental effect on physical/mechanical properties of the experimental adhesives. This could potentially help prevent secondary caries and increase the longevity of composite restorations when the adhesives are clinically available.
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