DIELECTRIC HEATING WITH HIGH-FREQUENCY CURVED PLATE APPLICATOR FOR BREAST CANCER TREATMENT
Keywords:
Dielectric heating, curved plate applicator, breast cancer treatmentAbstract
This paper presents the dielectric heating with high-frequency by using the straight and curved plate applicator to compare the electric field focusing on the tumor tissue in the breast phantom. The tumor tissue size provides 10, 20, and 30 mm was investigated heat distribution by using the bioheat transfer equation. The simulation result consists of return loss in dielectric materials, temperature treatment, and power loss density was analyzed in the tumor tissue on each coordinate. This applicator was stimulated by 2,450 MHz based on the electric field using the copper plate applicator. The tumor tissue in breast phantom was located at different coordinates in xy-plane and xz-plane. Simulation results show that the heating efficiency area could penetrate the internal tumor. The curved plate can be relocated and focused on tumor tissue. The rotation axis of the curved plate has been rotated in the vertical or horizontal axis of the breast phantom to heat up tumor tissue. The heat distribution area to the affected neighboring tissues has been decreased. The maximum heating area was close to the tumor tissue at the midpoint position between copper plates.
References
Asili, M., Chen, P., Hood, A.Z., Purser, A., Hulsey, R., Johnson, L., and Topsakal, E. (2015). Flexible microwave antenna applicator for chemo-thermotherapy of the breast. IEEE Antenn. Wirel. Pr., 14:1,778-1,781.
Converse, M., Bond, E.J., Hagness, S.C., and Veen, B.D.V. (2004). Ultrawide-band microwave space-time beamforming for hyperthermia treatment of breast cancer: a computational feasibility study. IEEE Transactions on Microwave Theory and Techniques, 52(8):1,876-1,889.
Correia, D., Kok, H.P., Greef, M.D., Bel, A., Wieringen, N.V., and Crezee, J. (2009). Body conformal antennas for superficial hyperthermia: the oimpact of bending contact flexible microstrip applicators on their electromagnetic behavior. IEEE T. Bio-Med. Eng., 56(12):2,917-2,926.
Elkayal, H.A., Ismail, N.E., and Lotfy, M. (2015). Microwaves 0for breast cancer treatments. Alexandria Eng. J., 54(4):1,105-1,113.
Fiser, O., Merunka, I., and Vrba, J. (2017). Optimization of microwave hyperthermia applicator system for deep placed tumors treatment in head and neck area. 2017 Progress In Electromagnetics Research Symposium - Spring (PIERS); May 22-25, 2017; St. Petersburg, Russia, IEEE, p. 1,733-1,738.
Giering, K., Lamprecht, I., Minet, O., and Handke, A. (1995). Determination of the specific heat capacity of healthy and tumorous human tissue. Thermochim. Acta, 251:199-205.
Iero, D.A.M., Crocco, L., and Isernia, T. (2014). Thermal and microwave constrained focusing for patient-specific breast cancer hyperthermia: A robustness assessment. IEEE T. Antenn. Propag., 62(2):814-821.
Iero, D.A.M., Isernia, T., Morabito, A.F., Catapano, I., and Crocco, L. (2010). Optimal constrained field focusing for hyperthermia cancer therapy: a feasibility assessment on realistic phantoms. Prog. Electromagn. Res., 102:125-141.
Jiao, S., Johnson, J. A., Tang, J., Tiwari, G., and Wang, S. (2011). Dielectric properties of cowpea weevil, black-eyed peas and mung beans with respect to the development of radio frequency heat treatments. Biosys. Eng., 108(3):280-291.
Kok, H.P. and Crezee, J. (2017). A comparison of the heating characteristics of capacitive and radiative superficial hyperthermia. Int. J. Hyperthermia, 33(4):378-386.
Kok, H.P., de Greef, M., van Wieringen, N., Correia, D., Hulshof, M.C., Zum Vörde Sive Vörding, P.J., Sijbrands, J., Bel, A., and Crezee, J. (2010). Comparison of two different 70 MHz applicators for large extremity lesions: simulation and application. Int. J. Hyperthermia, 26(4):376-388.
Martellosio, A., Pasian, M., Bozzi, M., Perregrini, L., Mazzanti, A., Svelto, F., and Bellomi, M. (2017). Dielectric properties characterization from 0.5 to 50 GHz of breast cancer tissues. IEEE T. Microw. Theory, 65(3):998-1,011.
Nguyen, P.T., Abbosh, A., and Crozier, S. (2015). Microwave Hyperthermia for Breast Cancer Treatment Using Electromagnetic and Thermal Focusing Tested on Realistic Breast Models and Antenna Arrays. IEEE Transactions on Antennas and Propagation, 63(10):4,426-4,434.
Nguyen, P.T., Abbosh, A.M., and Crozier, S. (2016). Thermo-dielectric breast phantom for experimental studies of microwave hyperthermia. IEEE Antenn. Wirel. Pr., 15:476-479.
Nguyen, P.T., Abbosh, A.M., and Crozier, S. (2017). 3-D focused microwave hyperthermia for breast cancer treatment with experimental validation. IEEE T. Antenn. Propag., 65(7):3,489-3,500.
Stang, J., Haynes, M., Carson, P., and Moghaddam, M. (2012). A preclinical system prototype for focused microwave thermal therapy of the breast. IEEE T. Bio-Med. Eng., 59(9):2,431-2,438.
Tang, Y., Jin, T., and Flesch, R.C.C. (2017). Numerical temperature analysis of magnetic hyperthermia considering nanoparticle clustering and blood vessels. IEEE T. Magn., 53(10):1-6.
van de Kamer, J.B., Van Wieringen, N., De Leeuw, A.A., and Lagendijk, J.J. (2001). The significance of accurate dielectric tissue data for hyperthermia treatment planning. Int J Hyperthermia, 17(2):123-42.
van Stam, G., Kok, H.P., Hulshof, M.C.C.M., Kolff, M.W., van Tienhoven, G., Sijbrands, J., and Crezee, H. (2017). A flexible 70 MHz phase-controlled double waveguide system for hyperthermia treatment of superficial tumours with deep infiltration. Int. J. Hyperthermia, 33(7):796-809.
van Wieringen, N., Wiersma, J., Zum Vörde Sive Vörding, P., Oldenborg, S., Gelvich, E. A., Mazokhin, V.N., and Crezee, J. (2009). Characteristics and performance evaluation of the capacitive Contact Flexible Microstrip Applicator operating at 70 MHz for external hyperthermia. Int. J. Hyperthermia, 25(7):542-553.
Wu, L., Cheng, J., Liu, W., and Chen, X. (2015). Numerical analysis of electromagnetically induced heating and bioheat transfer for magnetic fluid hyperthermia. IEEE T. Mag., 51(2):1-4.
