EFFICACY OF SODIUM BICARBONATE AND DETERMINATION OF HAEMATOLOGICAL PARAMETERS AGAINST FOOT-AND-MOUTH DISEASE VIRUS IN CATTLE

Authors

  • Deluwer Hossain Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh.
  • Ashit Kumar Paul Department of Medicine and Surgery, Faculty of Animal Science and Veterinary Medicine, Patuakhali Science and Technology University, Barisal-8210, Bangladesh.
  • Md Salahuddin Department of Biological Sciences, Sungkyunkwan University, Gyeonggi-do, 440-746, South Korea.
  • Md Mashiur Rahman Department of Livestock Services, Ministry of Fisheries and Livestock, People’s Republic of Bangladesh, Krishi Khamar Sarak, Farmgate, Dhaka-1215, Bangladesh.
  • Md Abdus Samad Department of Livestock Services, Ministry of Fisheries and Livestock, People’s Republic of Bangladesh, Krishi Khamar Sarak, Farmgate, Dhaka-1215, Bangladesh.
  • M Mahbub Mostofa Department of Pharmacology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh.
  • Md Alimul Islam Department of Microbiology and Hygiene, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh.
  • A Mustari Department of Physiology, Faculty of Veterinary Science, Bangladesh Agricultural University, Mymensingh-2202, Bangladesh.
  • MM Hossain Department of Anatomy, Histology and Physiology, Sher-e-Bangla Agricultural University, Dhaka-1207, Bangladesh.
  • Mohammad Showkat Mahmud Bangladesh Livestock Research Institute, Animal Health Research Division, Savar, Dhaka-1341, Bangladesh.

Keywords:

FMD virus, sodium bicarbonate, prophylaxis, therapeutic, blood parameter

Abstract

Foot-and-mouth disease (FMD) is the most economically important animal pathogen in Bangladesh. The present study was to investigate the effect of sodium bicarbonate against the FMD virus and determine the haematological parameters in cattle. In this study, 200 cattle were selected and divided into 5 groups in 7 different areas of Bangladesh to determine the preventive and therapeutic efficacy of sodium bicarbonate. Four groups of cattle were treated with sodium bicarbonate at 10 gm/L for a preventative dose and at 20 gm/L for a therapeutic dose and observed at 7 days’ intervals. All the blood parameters were studied on day 0 (pre-treatment), day 14, and day 21. The morbidity and mortality rates of the cattle were significantly (P < 0.001) reduced during the period of use of sodium bicarbonate as a prophylactic and therapeutic agent in the 4 groups of cattle. In evaluating the efficacy of sodium bicarbonate as a preventive measure for FMD at a dose rate of 10 gm/L, water is better than the therapeutic measure. These findings indicate that the oral administration and wash with sodium bicarbonate affected the tongue and foot for 10 days and, as a result, significantly decreased the morbidity and mortality of the cattle. This preparation also increased the differential leukocytes count of the blood as a prophylaxis dose and decreased the lymphocyte as a therapeutic dose in the cattle.

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Published

2026-08-28

How to Cite

Hossain, D., Kumar Paul, A., Salahuddin, M., Rahman, M. M., Samad, M. A., Mostofa, M. M., Islam, M. A., Mustari, A., Hossain, M., & Showkat Mahmud, M. (2026). EFFICACY OF SODIUM BICARBONATE AND DETERMINATION OF HAEMATOLOGICAL PARAMETERS AGAINST FOOT-AND-MOUTH DISEASE VIRUS IN CATTLE. Suranaree Journal of Science and Technology, 22(1), 43–50. retrieved from https://ph04.tci-thaijo.org/index.php/SUJST/article/view/14059

Issue

Vol. 22 No. 1 (2015): January - March

Section

Research Article