Serum tumor markers in the diagnosis of cholangiocarcinoma


  • Kawin Leelawat Department of Surgery, Rajavithi Hospital, Bangkok 10400, Thailand


Cholangiocarcinoma, CA19-9, CEA, CYFRA21-1, IL-6, MMP-7, MUC5AC, RCAS1


Cholangiocarcinoma is one of the most common causes of cancer-related death in Thailand. Unlike other kinds of solid tumors, a preoperative pathological diagnosis of cholangiocarcinoma is very difficult because of the location and the desmoplastic characteristic of this disease. Only by obtaining a proper diagnosis can the optimal treatment of a cholangiocarcinoma patient be assured. Therefore, identification of tumor markers in the serum would be beneficial in the clinical diagnosis and management of this disease. Here, we review the recent data concerning serum tumor markers, including CA19-9, CEA, CYFRA21-1, IL-6, MMP-7, MUC5AC, and RCAS1, for diagnosis of cholangiocarcinoma.


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How to Cite

Leelawat, K. . (2023). Serum tumor markers in the diagnosis of cholangiocarcinoma. Journal of Current Science and Technology, 1(2), 179–185. Retrieved from



Review Article