Probiotic properties of Lactobacillus pentosus GP6 isolated from fermented ground pork


  • Nattakan Dangmanee College of Oriental Medicine, Rangsit University, Patumthani 12000, Thailand


fermented ground pork, gastrointestinal pathogens, GP6, Lactobacillus pentosus, potential probiotic


Lactobacillus spp. is one of the lactic acid bacteria with probiotic properties.  This strain plays important roles for many fermented foods.  Lactobacillus pentosus GP6 isolated from fermented ground pork showed antimicrobial potential against bacterial gastrointestinal pathogens, including Enteropathogenic Escherichia coli (EPEC) DMST 30546, Pseudomonas aeruginosa, Salmonella Typhimurium and Shigella sonnei.  It was susceptible to all tested antibiotics except vancomycin.  L. pentosus GP6 survived in low pH and was tolerant to bile salt.  It exhibited good growth in simulated gastric and intestinal tracts.  This strain had a good autoaggregation and a high surface hydrophobicity.  Moreover, this lactobacillus showed coaggregation with EPEC DMST 30546 to affect its adhesion and colonization.  L. pentosus GP6 showed high adhesion ability to Caco-2 cell line and the adhesion of EPEC DMST 30546 to this cell line was decreased in the presence of this lactobacillus.  Overall, the results indicated L. pentosus GP6 is a potential probiotic for dietary supplement formulations.


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How to Cite

Dangmanee, N. . (2023). Probiotic properties of Lactobacillus pentosus GP6 isolated from fermented ground pork. Journal of Current Science and Technology, 8(1), 41–49. Retrieved from



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