The relationship of refractive error and glaucoma in a university eye clinic

Watanee Jenchitr; Matee Jaradaroonchay

Authors

Watanee Jenchitr Faculty of Optometry, Rangsit University, Patumthani 12000, Thailand
Matee Jaradaroonchay Faculty of Optometry, Rangsit University, Patumthani 12000, Thailand

Keywords:

angle-closure glaucoma, eye clinic, myopia, hyperopia, open-angle glaucoma, refractive error

Abstract

The Faculty of Optometry at Rangsit University performed a retrospective study using records from the eye clinic at Rangsit University (RSU) Healthcare. The objective of the study was to evaluate the relationships between refractive errors and glaucoma and between systemic diseases and glaucoma. Participants were patients attending the eye clinic between 2015 and 2019, aged 40-80 years, who had complete eye examinations and regular follow-up. The total number of subjects was 3,468 (mean age 60.19 ±10.63 years). The examination included measurement of the presenting and best-corrected visual acuity, auto and manifest refraction, applanation intraocular pressure measurement, gonioscopy, cup-to-disc ratio, nerve fiber layer analysis, and perimeter and central corneal thickness measurement. Glaucoma was diagnosed via standardized criteria of the American Academy of Ophthalmology. Cases of refractive error, expressed as spherical equivalent (SE), included 1,154 cases of myopia (mild, moderate and severe), 1,381 cases of hyperopia (mild, moderate and severe) and 359 cases of astigmatism. Subjects also included 302 emmetropic individuals, 139 subjects with pseudophakia and 133 individuals who had undergone refractive surgery. A total of 555 glaucoma cases (19.56%) were identified, including 354 cases of primary open-angle glaucoma (POAG), 50 instances of primary angle-closure glaucoma (PACG), 106 cases of normotension glaucoma (NTG), and 45 cases of secondary glaucoma (SOAG). Subjects with glaucoma-related conditions included 41 post-glaucoma surgery cases, 81 ocular hypertension (OHT) cases, 186 primary open-angle glaucoma-suspect (POAGS) cases, 178 individuals with primary angle closure (PAC) and 166 subjects who had undergone laser peripheral iridotomy (LPI). The results indicated that the prevalence of some types of glaucoma and glaucoma-related conditions (PAC, NTG, OHT and SOAG) increased with advancing age (p = 0.022, 0.001, 0.001, 0.021 respectively).

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